THYRAGE is a EC funded H2020 research project that will investigate the effects of thyroid hormone on a wide range of age-related diseases, including osteoporosis, osteoarthritis, neurological disorders and sarcopenia. Knowledge generated in this innovative project is needed to develop new strategies to prevent and treat these diseases in the elderly.

4th Hungarian Neuroendocrine Symposium

published: 31-05-2018 09:48
The Hungarian Neuroendocrine Symposium (MNSZ) held its 4th meeting May the 30th in Hajdúszoboszló, Hungary. The event was organized by THYRAGE partners, Prof. Csaba Fekete and Prof. Balázs Gereben from IEM HAS.

THYRAGE young investigator Richárd Sinkó (IEM HAS) presented their latest findings titled “Age-dependent processes of local thyroid hormone signalling in thyroid hormone action indicator (THAI) mice with nonthyroidal illness syndrome”.

The Hungarian Neuroendocrine Symposium could successfully reach most Hungarian neuroendocrinologists for the fourth time. The one-day long symposium was held in Hajdúszoboszló, Hungary in a friendly and cosy environment with a total of 72 guests. Young researchers were encouraged to give presentations in favour of senior scientists and questions from the audience were greatly appreciated: every question asked rewarded a token. These tokens increased the chance of winning a fancy multipipettor, the winning token was blindly drawn from a bowl.

THYRAGE young investigator Richárd Sinkó from the laboratory of Prof. Balázs Gereben showed the lab’s latest results achieved in collaboration with Prof. Csaba Fekete studying how local thyroid hormone economy adapts to massive metabolic challenges and how aging impacts the underlying mechanisms in brain areas responsible for central regulation of thyroid hormone signalling. One key conclusion is the age-dependent coexistence of tissues with local hypo-, eu- and hyperthyroid state in the same animal. The work is based on the group’s Thyroid Hormone Action Indicator (THAI) mouse holding a PCT of the European Patent Office and published recently in Endocrinology (doi: 10.1210/en.2017-00582). The results presented highly contribute to the THYRAGE activity of IEM HAS and highlight the importance of evaluating local thyroid hormone signalling both in research and diagnostics.

The symposium was a great success regarding both the scientific program and atmosphere. The organizers are thankful for all participants and funds and plan to continue the biannual event in a similar fashion.

Program can be found here