The Joint Research Unit "Evolution of Endocrine Regulations" is affiliated with the CNRS and the National Muséum of Natural History. Research focuses on nuclear receptors and development, exemplified by its role in the FP6 project CRESCENDO and FP7 projects SWITCHBOX and HUMAN. Besides being involved in the Exploitation Monitoring Board, main focus of CNRS will be the control of TH availability in the adult neural stem cell niche and cell specific delivery of TH modulators in the stem cell niche, using both in vivo delivery methods and in vitro neurosphere cultures.
Prof. Barbara Demeneix
Prof. Barbara Demeneix has a noteworthy track-record in basic and translational research (over 170 publications in endocrinology and physiology) as well as in leading and managing international and national research consortia. She was coordinator (till February 2015) of SWITCHBOX, an EU Integrated Project addressing the role of central, hypothalamic control of metabolism in ageing. She was one of the recipients of the CNRS medal for Innovation in 2014 and the Nature Mentoring Award for France in 2011.
Dr. Sylvie Remaud
Dr. Sylvie Remaud has TH regulation of the neural stemm cell niche, notably commitment of precursor populations during aging, as main research focus.