THYRAGE is a EC funded H2020 research project that will investigate the effects of thyroid hormone on a wide range of age-related diseases, including osteoporosis, osteoarthritis, neurological disorders and sarcopenia. Knowledge generated in this innovative project is needed to develop new strategies to prevent and treat these diseases in the elderly.

22nd Annual Symposium Dutch Thyroid Research Foundation

published: 11-06-2018 10:08
On the 8th of June THYRAGE investigator Domenico Salvatore was invited to present his work on thyroid hormones and muscle function at the 22nd Annual Symposium of the Dutch Thyroid Research Foundation at West-Indisch huis in Amsterdam, the Netherlands. From the LUMC Nicolien van Vliet and Ferdinand Roelfsema also attended the symposium.


The symposium was dedicated to Theo Visser, who has contributed greatly to the thyroid field and passed away unexpectedly last March.

The first session provided an overview of his work, presented by Robin Peeters and Edward Visser (Eramsus MC, the Netherlands). During the second session, Heike Heuer (Dusseldorf, Germany) showed the impressive work her laboratory has conducted on the effects of tissue specific MCT8 knock-out mice on alterations in the hypothalamic-pituitary-thyroid axis. Stefan Groeneweg (Erasmus MC, the Netherlands) shared the promising results of the first multi-center trial of TRIAC in patients with MCT8 defects. The last session before lunch was about the effects of trace elements on thyroid homeostasis; the effects of selenium were discussed by Lutz Schomburg (Charité Universitätsmedizin, Germany) and the effects of iodine deficiency in pregnancy were presented by Sara Bath (University of Surrey, UK). After lunch, the symposium continued with a session on thyroid hormones and haematology. Anne van der Spek (AMC, the Netherlands) presented her work on the effects of thyroid hormone levels on macrophages, and Anja van Gucht (Erasmus MC, the Netherlands) spoke about the mechanisms underlying the relationship between hypothyroidism and anaemia. Romana Netea-Maier (UMCN, the Netherlands) discussed recent findings on the effects of thyroid function on the immune system. In the final session of the day, the effects of thyroid hormones on skeletal muscle were presented by Domenico Salvatore (University of Naples, Italy). He was followed by the two final speakers Nils Bömer (UMCG, the Netherlands) and Layal Chaker (Erasmus MC, the Netherlands) speaking about the relationship between thyroid hormones and the heart.

It was an inspiring and well-organized symposium covering multiple areas of thyroid related research currently conducted in the Netherlands and elsewhere in Europe!

Full program