THYRAGE is a EC funded H2020 research project that will investigate the effects of thyroid hormone on a wide range of age-related diseases, including osteoporosis, osteoarthritis, neurological disorders and sarcopenia. Knowledge generated in this innovative project is needed to develop new strategies to prevent and treat these diseases in the elderly.

20th Annual Symposium Dutch Thyroid Research Foundation

published: 24-06-2016 09:22
On June 17th, THYRAGE investigators Graham Williams and Duncan Bassett had the privilege of speaking at the 20th Annual Symposium of the Dutch Thyroid Research Foundation, which took place at the Trippenhuis in Amsterdam. The meeting was a great success and attended by colleagues from Leiden including THYRAGE investigator Diana van Heemst and members of her laboratory.


It was a great opportunity to meet with collaborators from Amsterdam (Anita Boelen and Eric Fliers), who will be collaborating with the THYRAGE project in the measurement of deiodinase enzyme activity and measures of thyroid hormones by HPLC. The scientific content of the meeting was highly relevant to the research aspirations of THYRAGE and included clinical discussion of the genetic contribution to control of the HPT axis (Robin Peeters, Rotterdam) and analysis of the physiological basis, pitfalls and possible role of T4/T3 combination therapy in the treatment of hypothyroidism (Graham Williams, Imperial College London & Eric Fliers, Amsterdam). Duncan Bassett (Imperial College London) discussed the role of alternative splicing of thyroid hormone receptor alpha in the control of bone development and maintenance in a stimulating basic symposium on hormone action that included presentations from Marcel Meima (Rotterdam) and Jens Mittag (University of Lubeck).

Additional clinical and basic contributions from younger scientists and PhD students continued the high quality of the meeting, that was rounded off by an excellent clinical discussion of the possible role of molecular analysis in the management of differentiated thyroid cancer (Ralf Paschke, University of Calgary).

Overall, the Dutch Thyroid Research Foundation Committee (Dop Simonides, Thera Links, Jan Smit, Anita Boelen) is to be congratulated on an outstanding day, superb hospitality and the numerous opportunities for THYRAGE to meet up with old friends and make new ones. The thyroid community is thriving in Europe and THYRAGE is proud to be at the centre of the action!!

Meeting programme