THYRAGE is a EC funded H2020 research project that will investigate the effects of thyroid hormone on a wide range of age-related diseases, including osteoporosis, osteoarthritis, neurological disorders and sarcopenia. Knowledge generated in this innovative project is needed to develop new strategies to prevent and treat these diseases in the elderly.

Our Mission

To achieve our mission, over a period of five years (2016-2021), experts from five European countries are joining forces in THYRAGE: resetting the THYRoid axis for prevention of AGE-related diseases and co-morbidities.

Our Partners

  • Leiden University Medical Center, Leiden, The Netherlands
  • CNRS, Paris, France
  • Imperial College London, London, United Kingdom
  • University of Naples, Naples, Italy
  • The Institute of Experimental Medicine, Budapest, Hungary
  • Pepscan, Lelystad, the Netherlands


A combined meeting for the TRUST and IEMO-80 plus thyroid trial was organised on the 19th and 20th of May 2019 in Leiden, the Netherlands. THYRAGE investigators Diana van Heemst, Rudi Westendorp (also one of the principal investigators of TRUST) and Nicolien van Vliet were among the attendants.